Conflicts of interest in clinical research
This dissertation conducted by our researcher Camilla Hansen Nejstgaard studies the impact of conflicts of interest on results, conclusions, and recommendations in different types of clinical research.
Clinical research studies, such as randomised trials and systematic reviews, have profound impact on patient care. It is therefore essential, that such studies are trustworthy. Quite often, clinical research is either funded by drug or device companies or written by authors that have ties with individual companies; for example by being on a company’s speakers’ bureau or advisory board. Such relationships create conflicts of interest. It is an ongoing concern whether conflicts of interest impact on clinical research and consequently on patient care.
The PhD describes and analyses the impact of conflicts of interest on results, conclusions, and recommendations in different types of clinical research. It is based on three sub-studies that focuses on 1) Cochrane systematic reviews, 2) non-primary research studies such as clinical guidelines, committee meetings, opinion pieces (e.g. editorials), and non-systematic reviews, and 3) randomised trials.
The PhD oral defence will take place on 17th September at 14-16 (CET) in room 25.111 at J.B Winsløws Vej, 5000 Odense. It can also be attended through Zoom via this link: https://syddanskuni.zoom.us/j/62957380851
Read Camilla’s interview about the Cochrane review on financial and non-financial conflicts of interest in clinical guidelines, advisory committee reports, opinion pieces, and non-systematic reviews as part of her PhD thesis. You can also find this Cochrane review investigating financial conflicts of interest in systematic reviews.